ZoGuard Plus for Dogs

ZoGuard Plus for Dogs

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Product Description

Ultimate Guide to ZoGuard Plus for Dogs

Meet the 3-to-1 Parasite Killing Liquid: ZoGuard Plus for Dogs!

ZoGuard Plus for Dogs is a veterinarian-recommended dog medication that protects your dogs from dangerous external parasites - fleas, ticks, and chewing lice. ZoGuard Plus for Dogs is a monthly, spot-on application therapy that also prevents Lyme disease. ZoGuard Plus for Dogs guarantees pup comfort.

How does ZoGuard Plus for Dogs work?

ZoGuard Plus for Dogs is a medication with the two active ingredients that are also in Frontline Plus for Dogs - Fipronil and (S)-methoprene - that kill chewing lice, ticks, and attacks the flea's life cycle. ZoGuard Plus kills the parasites on contact by storing itself in the oil glands in your pet's skin and hair follicles continuously for the next 30 days.

Fipronil for dogs is a phenylpyrazole insecticide that disrupts the insect's central nervous system by blocking the GABA-gated chloride channels that regulate cellular excitability to the contaminated insect's neuromuscular system and glutamate-gated chloride (GluCl) channels that control movement, feeding, and behavior.

(S)-methoprene is an insecticide chemical that controls hatching eggs, obstructs the development of the immature flea (i.e., flea pupae and larvae) into a breeding adult, and proper growth into a healthy viable adult flea. Together, these active ingredients deter parasites and put a stop to the flea life cycle.

How is ZoGuard Plus for Dogs administered?

ZoGuard Plus for Dogs is administered topically once a month and protects your dog for the next 30 days.

How to apply ZoGuard Plus for Dogs:

  1. Remove the individual tube from the packaging.
  2. With scissors, cut the notched side with lines after turning it away from your face.
  3. Part your dog's hair at between the shoulder blades.
  4. Apply the entire contents to one spot on the dog's skin.
Body Weight Box Color Fl. Oz. Per Tube
4 - 22 lbs. Orange 0.069
23 - 44 lbs. Purple 0.135
45 - 88 lbs. Red 0.273
89 - 132 lbs. Green 0.408

Available are 3 or 6 monthly doses.

What are the precautions of which you should be aware?

The following should be discussed with your veterinarian before using ZoGuard Plus or other pesticide product treatment:

  • Some medications cause negative interactions with ZoGuard or its ingredients
  • Breeding, pregnant, lactating, debilitating, or geriatric dogs
  • Undergoing skin dermatitis medications
What is ZoGuard Plus for Dogs' potential side effects of which you should be aware?

Temporary irritation may occur. Side effects are rare but any that occur should be discussed with your veterinarian.

Frequently Asked Questions
  1. What do the ZoGuard Plus for Dogs reviews say?

    ZoGuard Plus for Dogs reviews rate 4.5 out of 5 stars. Most reviewers say that ZoGuard Plus for Dogs is a highly recommended flea and tick treatment with an easy application that they trust for their furry best friend.

  2. How long does it take for ZoGuard Plus to work?

    ZoGuard Plus will kill 100% of fleas within 4 to 12 hours of the application. If there are eggs that have not yet hatched, then they would not have been exposed to ZoGuard Plus's active ingredients.

  3. How long does it take for ZoGuard Plus for Dogs to dry?

    Be sure your dog is dry before application, and keep your dog dry for 24 hours after application. Do not bathe your dog for 24 hours after application. Separate the treated dog from all other dogs, cats, and children for 24 hours after treatment has been applied. Do not apply more frequently than once every four weeks.

  4. Is ZoGuard Plus for Dogs for puppies?

    ZoGuard Plus for Dogs can be administered to puppies that are at least 8 weeks of age and weigh 4 pounds.

Concluding Thoughts

The most important thing that you should know about ZoGuard Plus for Dogs is its power to protect your dog from tiny external parasites and dangerous diseases that are connected to them.

DISCLAIMER: FDA law restricts ZoGuard Plus for Dogs only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if this is a suitable product for your pet and your home.

Side Effects & Warnings

For external use only. Although rare, some sensitivities can occur when using pesticide products on dogs. Speak with your vet to discuss any current medications and how it may react with ZoGuard Plus for Dogs. Follow manufacturer instructions to ensure an overdose does not occur, as overdosing can cause serious illness or death. Speak with your vet if your dog is pregnant, nursing, using other medications, aged, or has any debilitating condition before treating your dog with ZoGuard Plus. Dogs undergoing any skin dermatitis medications should speak with your vet before applying ZoGuard Plus for Dogs.


Fipronil..................9.80% (S)-methoprene....8.80%


Once removed from packaging, separate an individual tube from its grouping. Keep notched side of tube pointed up and away from your face and body. With scissors, cut the notched side with lines.

Using the cut end of the tube part your dog’s hair at the shoulder blades, and apply the treatment by applying directly to your dog’s skin. Dose every 4 weeks, do not apply more treatments less than 4 weeks apart.

Temporary irritation may occur – supervise your dog and if any reactions persist, speak with your vet.

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