Revolution Plus for Cats

Revolution Plus for Cats

Requires Rx

Free delivery


Every time a new member signs up, we will donate a FREE membership to a Best Friends adopted animal. Best Friends is America's largest animal sanctuary.

Get all these benefits with $139.95 annual membership


Our customers typically save close to $200/yr when purchasing preventatives as members of PetPlus.

PetPlus is a membership plan that gives you wholesale pricing on preventatives, supplements and speciality foods.
With Free Shipping always, no minimums.

Why Become A Member? Additional Ways To Save With PetPlus

Typical Annual Savings "For Your Pet

Typical Annual Cost $40 $190 $95 $112 $200
PetPlus Annual Cost $12 $110 $55 $68 $150
  Sample Annual PetPlus Savings $28 $80 $40 $44 $65
Typical Annual Cost
PetPlus Annual Cost
Sample Annual PetPlus Savings

We're Here to Help You Every Step of the Way

average savings

$242 / YR

Wholesale Prices on Pet Medication & Supplements
Free 24/7 Pet Help provided by whiskerDocs
Wholesale Prices on RX & Premium Foods and Treats
Convenient Medication Pickup Option
Free Delivery on Medication
Product Description

Ultimate Guide to Revolution Plus for Cats

Meet the 6-in-1 Parasite Protector: Revolution Plus for Cats!

Revolution Plus for Cats is the #1 veterinarian choice for cat protection against internal and external dangerous parasites. Revolution Plus is a monthly treatment that is a 6-in-1 topical solution that also prevents fatal heartworm disease. Revolution Plus for Cats ensures that your kitty is in their healthiest condition and the happiest you!

How does Revolution Plus work?

Revolution Plus for Cats' active ingredients is Selamectin and Sarolaner that both interrupt a parasites' neuromuscular system and primary behavior.

Selamectin is an avermectin antiparasitic agent that effectively treats parasites inside and outside of felines by blocking the transmission of electrical activity in invertebrate neuromuscular systems in nematodes (e.g., roundworms) and muscle cells in arthropods leading to their paralysis and ultimately their death.

Sarolaner is an insecticide that blocks GABA- and glutamate-gated chloride channels in the nervous system of insects and acarine (e.g., mites and ticks). This blockage of these nerve receptors results in increased nerve stimulation and the death of the target parasite.

How is Revolution Plus for Cats administered?

Revolution Plus is administered topically through a spot-on treatment once a month and protects your cat for the next 30 days. Open the tube's cap, part the hair on the base of the cat's neck between the shoulder blades, place the tube's tip on the cat's skin, and empty the entire contents of the tube in one spot.

Depending on the cat's body weight, there are three different colors of boxes of Revolution Plus of Cats with different mL of contents and different ratio between the two active ingredients. See the dosage chart below:

Body Weight Box Colors Tube Volume (mL) Selamectin (mg/tube) Sarolaner (mg/tube)
2.8 - 5.5 lbs. Gold 0.25 15 2.5
5.6 - 11 lbs. Orange 0.50 30 5
11.1 - 22 lbs. Green 1 60 10

Revolution Plus for Cats 6 pack and 3 pack in every box are available.

What are the precautions of which you should be aware?

Use with caution in cats with a history of neurological disorders. The safe use of Revolution Plus hasn't been evaluated in kittens under 8 weeks of age or in breeding, pregnant, or lactating cats.

What are the potential side effects of Revolution Plus for Cats of which you should be aware?

Revolution Plus for Cats' most common adverse reactions reported is lethargy and anorexia. The active ingredient Sarolaner can be associated with adverse reactions such as tremors, seizures, and ataxia (a degenerative disease that is responsible for coordination).

Frequently Asked Questions
  1. What does the Revolution Plus for Cats reviews say?

    Revolution Plus for Cats reviews rate 5 out of 5 stars. Most reviewers say that Revolution Plus for Cats is the safest option and #1 veterinarian recommended and safest flea treatment for a cat and home infestation.

  2. What is the difference between Revolution and Revolution Plus for Cats?

    Revolution is effective against five kinds of parasites. It kills and protects cats from fleas, ear mites, chewing lice, the intestinal worms, roundworms, and hookworms. Both medicines prevent heartworm disease. Revolution Plus adds the second active ingredient Sarolaner with the added ability to eliminate ticks.

  3. What is the Revolution Plus for Cats dosage?

    Know that your cat's weight affects the box and dosage that you choose. Available are monthly tubes for Revolution Plus for Cats 2.8 - 5.5 lbs, Revolution Plus for Cats 5.6 - 11 lbs., and Revolution Plus for Cats 11.1 - 22 lbs. Your choice will provide a comparable dosage (i.e., amounts of two active ingredients Selamectin and Sarolaner).

  4. How long does Revolution Plus for Cats work in clinical studies for fleas?

    In a well-controlled laboratory study, Revolution Plus for Cats starts to kill fleas within 12 hours of treatment and kills more than 98% of fleas within 24 hours. During the next 30 days, fleas start to be killed at 6 hours, and more than 93.8% of fleas within 12 hours after application.

  5. Is Revolution Plus for Cats for kittens?

    The medication is for kittens that are at least 8 weeks of age and weigh 2.8 pounds.

Concluding Thoughts

The most important thing that you should know about Revolution Plus for Cats is its power to protect your cats from internal and external tiny parasites and the dangerous heartworm disease.

DISCLAIMER: FDA law restricts Revolution Plus for Cats only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if this is a suitable product for your pet and your home. Approved by FDA under NADA 141-502.

Side Effects & Warnings

Use with caution in cats with a history of neurologic disorders. The safe use of Revolution Plus hasn't been evaluated in kittens under 8 weeks of age, nor has the safety of Revolution Plus been evaluated in breeding, pregnant, or lactating cats.


15mg selemectin, 2.5mg sarolaner.


As this is a prescription, please consult for directions with your pets veterinarian. Firmly press the cap down to puncture the seal on the tube. A clicking sound will confirm that the seal has been punctured. Remove the cap and check to ensure the tip of the tube is open. Part the hair on the back of your cat at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and empty the entire contents of the tube in one spot. Check to make sure the tube is empty 2.8-5.5 lbs Apply contents of one 0.25 ml tube once a month (Gold). 5.6-11 lbs Apply contents of one 0.5 ml tube once a month (Orange). 11.1-22 lbs Apply contents of one 1 ml tube once a month (Green).

Need Help? Call 1-866-893-0306