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Product Description

Ultimate Guide to Profender

Meet the One-Time Topical Cat Dewormer: Profender!

Profender is a vet-recommended dewormer for cats that provides a one-time topical deworming treatment. This exclusive product is administered on your cat's skin with an easy-to-use applicator that eliminates parasitic worms (i.e., tapeworms, roundworms, and hookworms) all at once, guaranteeing a comfortable and lovable condition.

How does Profender work?

Profender is a medication with two powerful active ingredients - Emodepside and Praziquantel. Emodepside is only found in Profender for cats and is effective against adult and immature stages of roundworms and hookworms.

Praziquantel is a prescription anthelmintic (de-wormer) that expels anti-parasitic worms like trematodes (e.g, tapeworms). Praziquantel is also an Insect Growth Regulator (IGR) that inhibits newly hatched insect larvae from reaching adulthood or reproducing.

After one treatment, all of the worms (i.e., adult tapeworms, roundworms, and hookworms, as well as immature roundworms and hookworms) will be expelled through the cat's feces.

How is Profender administered?

Profender is a liquid topical solution that is administered with a spot-on treatment with single-dose efficacy. According to the cat's weight, a customer will be able to choose the appropriate size and box with one full tube of Profender medication contents.

The recommended dosage is 1.36 mg per pound of Emodepside and 5.45 mg per pound of Praziquantel. See the dosage chart below:

Cat Weight & Size Color Dosage (mL) Emodepside (mg) Praziquantel (mg)
2.2 - 5.5 lbs. (Small) Blue 0.35 7.5 30.0
5.5 - 11 lbs. (Medium) Orange 0.70 15.0 60.1
11 - 17.6 lbs. (Large) Purple 1.12 24.0 96.1
Cats that weigh over 17.6 pounds should be treated with the appropriate mL tube amount.

The medication is applied directly to the base of the cat's neck. Make sure that it is not being applied to damaged skin or if the hair is wet. Place the opened applicator on the cat's exposed skin and squeeze the entire contents there. Only if a second application is needed due to a new infection, wait only after 30 days.

What are the precautions of which you should be aware?

Consult your veterinarian about using cat deworming products and about all of the medications that your cat is already taking. Flea and tick medications or preventatives have negative interactions with Profender for cats.

Sick or debilitated cats are cautioned to use the product. Pregnant women are cautioned to touch or apply the product to their cat. Children are cautioned to touch or even come into contact with your cat until after 24 hours after application.

What are side effects of Profender for cats that you should be aware of?

Profender for cat's most common adverse reactions reported are licking and excessive grooming at the treatment site, which can cause hypersalivation or vomiting. Scratching, hypersalivation, lethargy, hair loss, anxiety, vomiting, and diarrhea are very rare reactions.

Frequently Asked Questions

What is Profender for Cats?

Profender for cats is a deworming medication. It is a one-time topical solution for cats and kittens that are affected by worms. A single topical dose of the Profender and you can help with the treatment of all sorts of worms in your cats, including intestinal worms, tapeworms, and hookworm infections.

Does Profender Work?

Yes, Profender works, and it has been clinically tested and proven by experts in the field.

Studies suggest that Profender is very effective when used to treat and control infections caused by worms. It showed great results when it came to dealing with tapeworm infections. Profender also resulted in a 90 percent success rate where there was no roundworm or tapeworm infection after it was administered to the cats.

How Fast Does a Profender Work?

A Profender works quite fast usually within 24 to 48 hours.

For tapeworm infections, the Profender takes effect within 24 hours of applying. On the other hand, for other types of worms like roundworms or intestinal worms, it takes effect within 48 hours of applying.

How To Apply Profender to Cats?

Profender is a topical solution that is applied to the cat's neck region. To be more specific, cat owners need to administer the Profender directly to the base of the cat's neck.

Profender dosages can vary from 0.35 mL to 1.12 mL, and the amount you have to administer depends on the weight of your cat. To apply the Profender, locate the base of the cat's neck. Then, squeeze the contents of the applicator onto the exposed skin. Use with caution; make sure the medication is not coming in contact with damaged skin. Follow the vet's prescription if you are not sure how, or whether or not to apply the Profender.

Does Profender for Cats Kill Fleas?

No, Profender for cats does not kill fleas.

While it may be administered topically, the Profender gets absorbed by the cat's skin. It then deals with your cat's internal parasites. However, the Profender does not offer any sort of protection, nor does it help kill external parasites like fleas.

How Long for a Profender to Work?

It takes 24 to 48 hours for a Profender to work.

In normal conditions, the medication will take effect within 24 hours of applying in the case of tapeworms. For all other types of worms, it needs at least 48 hours to take effect. You do not have to wait for a long period to see whether or not the medication is working.

Is Profender Safe for Cats?

Yes, Profender is safe for cats, both adults as well as kittens.

However, cat owners need to be careful and make sure that their cats do not lick the medicine. Hence, the treated cats need to be isolated from other cats or pets inside the house until the medicine dries. You might want to use a cone for your cat if it has a habit of licking itself all the time.

Can You Use Profender and Revolution at the Same Time?

Yes, you can use Profender and Revolution at the same time.

Revolution is a flea treatment medication for cats. It can be used alongside Profender. However, it is better to use the two different types of medications at least two days apart.

Does Profender Kill Ear Mites?

Yes, Profender can kill ear mites.

Profender is proven to be very effective against roundworms, hookworms, and tapeworms. It has also shown great promise when it comes to killing ear mites. So you should feel free to use Profender for killing ear mites without any worry.

How Long Does Profender for Cats Last?

Profender for cats lasts two weeks from the time it has been administered.

After two weeks, if the cat catches worms, you will again have to deworm through the Profender treatment or any other deworming treatment for cats.

How Often to Apply Profender for Cats?

Profender needs to be applied every time your cat has worms.

You need to understand the Profender is a purge dewormer, meaning that is an instantaneous killer when it comes to worms. However, it is not a vaccine or a worm-preventing dosage. Hence, regular applications will only be required if your cat continues to get the worms, even after it has been treated for them.

So even after you are done applying the Profender, your job is not done. You then have to make sure that your cat does not come in contact with worms again. Otherwise, you will have to repeat the Profender treatment.
Concluding Thoughts

The most important thing that you should know about Profender is its one-time use treatment to expel internal parasitic worms - tapeworms, roundworms, and hookworms - from your cat. Forget about pills! Just apply a few drops on your cat's skin and you are that much closer to a worm-free kitty!

DISCLAIMER: FDA law restricts Profender only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Ask your veterinarian if it's a good idea to treat all of the animals in your household to control intestinal parasites.

Side Effects & Warnings

Consult your veterinarian regarding the diagnosis of worms before administering. Use with caution in sick or debilitated cats. Keep out of reach of children. Pregnant women or women who may become pregnant should avoid direct contact with, or wear disposable gloves when applying this product. Allow 24 hours after application before letting children come into contact with your cat.

Let your veterinarian know before combining with other medications, especially flea and tick prevention.


Praziquantel and Emodepside


Dosage runs according to your cats weight, typically one full tube is applied directly to your cats skin.

Make sure you’re applying to exposed skin with the tip directly and lifting tube away from the skin before releasing pressure on the tube.

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