Pilocarpine

Pilocarpine

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Product Description

Glaucoma can be scary for your pet. The pain and pressure caused by the condition is hard to ignore. Ask your veterinarian about Pilocarpine. It's a miotic agent used in the treatment of canine primary glaucoma and can help relieve the pressure in your dog's eyes by allowing fluid to drain more easily. And it can be used before or after surgery.

Pilocarpine is a medication primarily utilized in ophthalmology for the treatment of neurogenic keratoconjunctivitis sicca, a type of dry eye syndrome resulting from nerve dysfunction, and for diagnosing issues related to cranial nerve III.

While primarily intended for use in humans, pilocarpine is often prescribed off-label for veterinary purposes, particularly in dogs and cats. Its off-label use in veterinary medicine includes treating dry eye or glaucoma and diagnosing cranial nerve lesions.

  • Administration -The administration of pilocarpine varies depending on the condition being treated. For dry eye treatment, it is administered orally, often as a liquid solution mixed with food. Conversely, for glaucoma treatment or cranial nerve III diagnosis, it is applied topically, directly onto the eye.

  • Dosage -Pet owners should follow the veterinarian's prescribed dosage instructions closely. If a dose is missed, it should be administered as soon as remembered, but doubling up on doses should be avoided.

  • Side Effects -Potential side effects of pilocarpine use in pets include vomiting, diarrhea, increased salivation, increased urination, coughing, pulmonary edema, irritation at the application site, redness, squinting, cloudiness in the eye, and the development of irreversible constricted pupils with chronic eye use.

  • Duration of Effects -Pilocarpine typically begins to take effect within 1 to 2 hours of administration, and its effects typically cease within 24 hours.

  • Contraindications -Pilocarpine should not be used in pets with known allergies to the medication or in dogs with glaucoma stemming from uveitis or lens luxation. Caution should be exercised when using pilocarpine in pregnant or nursing pets.

  • Drug Interactions -While there are no specific known drug interactions with pilocarpine, pet owners must inform the veterinarian about all medications, including supplements and herbal therapies, that their pet may be taking.

Pet owners should closely monitor their pets for any signs of side effects following pilocarpine administration. Veterinarians may also regularly monitor tear production, eye pressure, and overall eye condition. In the event of an overdose or adverse reaction to pilocarpine, pet owners should contact their veterinary office immediately or follow the provided instructions for accessing emergency veterinary care.

Pilocarpine should be stored at controlled room temperature and protected from moisture, light, and freezing to maintain its efficacy.

The medication is not recommended in treating secondary glaucoma in dogs. Pilocarpine is for topical use only and should not be given orally. Before applying eye drops, make sure that your hands are washed thoroughly. Use the eye dropper with caution; the dropper tip should not come in contact with the eyes or the surface of the skin to avoid contaminating the medicine. Animals might develop initial irritation when the medication is administered; though, in very rare instances, only can these turn severe.

Though the medicine is not approved for treatment in animals, pilocarpine is a widely prescribed drug by veterinarians for use in dogs. The suggested dosage of medication would be one drop of pilocarpine 1% eye drops in the infected eye/s, thrice a day.

Side Effects & Warnings

Pilocarpine can cause local irritation when first used. Pilocarpine may cause systemic effects including vomiting, diarrhea and increased salivation.

Pilocarpine should not be used in secondary glaucoma. Wash hands before administering eye drops. Do not touch the dropper tip to the skin or eye.

Ingredients

Pilocarpine 1% is a miotic agent in veterinary medication indicated for the treatment of primary glaucoma in dogs. The medication is also found effective in the management of intraocular pressure related complications in animals. The drug has shown proven results in the clinical tests conducted in labs. The active ingredient present in the medication is pilocarpine, which is a cholinergic alkaloid that helps in decreasing the pressure mounting inside the eye ball. The drug can be obtained only by prescription from a licensed veterinarian, and is available as suspension eye drops.

Pilocarpine Hydrochloride 20 mg

Preservatives added:
Benzalkonium Chloride 0.01%

Other ingredients:
Monobasic Sodium Phosphate, Hypromellose, Edetate Disodium, Dibasic Sodium Phosphate, Purified Water. Sodium Hydroxide and/or Hydrochloric Acid may be added to adjust pH

Directions

Use as directed by your veterinarian.

The usual dose used to treat primary glaucoma in dogs is 1 drop in the effected eye(s) 3 times a day. Do not use the eye drop if it is discolored or has particles in it.

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