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Product Description

Lysodren is a treatment option for dogs that have been diagnosed with canine Cushing's disease. This medication has two phases: a "loading" phase and a "maintenance" phase. The combination of the medication's two phases allows for better care of your dog's disease so he or she can be feeling like normal in no time.

Lysodren is a perfect treatment option as it is kind to your wallet. In addition, Lysodren is incredibly easy to administer to your dog. This treatment option is not a shot or a pill that you have to force your dog to swallow by hiding it in its food. There is no need to tempt your dog to take its medication in numerous unhealthy treats as this medication comes in a convenient chewable tablet.

Do not use the drug on animals that are hypersensitive to mitotane, which is the active ingredient present in the medicine. The medication should not be tried in pregnant as well as nursing animals. Mitotane has a tendency to interact when used with insulin or spironolactone and in certain other combinations of medicines. It would be wise to inform the veterinarian of the medication that the pet is currently receiving. Personal protection is also important in dealing with the medication, as mitotane is cytotoxic to humans. If in case the drug comes in contact with the skin it has to be washed off immediately. Instances of medication overdose could be fatal if not attended to.

The medication has side effects in animals that might lead to Addison's disease or its symptoms such as decreased appetite, vomiting and diarrhea, lethargy, weakness etc. Observe the symptoms and in the event of severe reactions to the medicine, supplement with glucocorticoids like prednisone.

Lysodren is the Generic Alternative to Mitotane.

Side Effects & Warnings

In treating Cushing's Disease, lysodren may erode the adrenal cortex so far as to create a cortisone defiency, either temporarily or irreparably. The latter case is referred to as Addison’s disease. Symptoms include loss of appetite, vomiting, diarrhea , weakness and drowsiness. Contact a veterinarian immediately if symptoms are observed.

This medication should not be used in animals that are allergic to it. Do not use in pregnant or nursing animals. Use with caution in animals with kidney or liver disease. Use caution when used with insulin or spironolactone.




Consult your veterinarian for dosing and accompanying treatment, and for caution regarding drug interaction. Be prepared to monitor your pet regularly with blood tests.

Lysodren follows a treatment regimen of a "loading phase" followed by a "maintenance phase" in order to help you manage your pet's illness.

Do not handle Lysodren with your bare hands, particularly if you are pregnant or trying to get pregnant.

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