Iverhart Plus

Iverhart Plus

Requires Rx

Free delivery


Every time a new member signs up, we will donate a FREE membership to a Best Friends adopted animal. Best Friends is America's largest animal sanctuary.

Get all these benefits with $139.95 annual membership


Our customers typically save close to $200/yr when purchasing preventatives as members of PetPlus.

PetPlus is a membership plan that gives you wholesale pricing on preventatives, supplements and speciality foods.
With Free Shipping always, no minimums.

Why Become A Member? Additional Ways To Save With PetPlus

Typical Annual Savings "For Your Pet

Typical Annual Cost $40 $190 $95 $112 $200
PetPlus Annual Cost $12 $110 $55 $68 $150
  Sample Annual PetPlus Savings $28 $80 $40 $44 $65
Typical Annual Cost
PetPlus Annual Cost
Sample Annual PetPlus Savings

We're Here to Help You Every Step of the Way

average savings

$242 / YR

Wholesale Prices on Pet Medication & Supplements
Free 24/7 Pet Help provided by whiskerDocs
Wholesale Prices on RX & Premium Foods and Treats
Convenient Medication Pickup Option
Free Delivery on Medication
Product Description

Comprehensive Dog Guide to Iverhart Plus

Meet Internal Parasite Preventer: Iverhart Plus!

Iverhart Plus is a prescription-only dog medication that easily and effectively protects your dogs from internal parasitic worms - heartworm, hookworm, roundworm, and other parasites. Iverhart Plus is a monthly, pork-liver flavored chewable oral tablet that also prevents fatal heartworm disease.

How does Iverhart Plus work?

Iverhart Plus is a medication with two active ingredients - Ivermectin and Pyrantel Pamoate.

Ivermectin is an anti-parasitic agent that treats infections caused by roundworms, threadworms, and other parasites. Ivermectin stimulates the excessive release of neurotransmitters thus causing neurological damage which results in the parasite's paralysis and eventual death.

Pyrantel Pamoate is an anthelmintic (i.e., dewormer) that uses a unique paralysis effect against intestinal parasitic worms that attach themselves to the host's intestinal tract with its tiny teeth or suckers. The ingredient acts as a neuromuscular blocker to relax the parasite's grip, is paralyzed, and is effectively eliminated from its unaffected host.

How is Iverhart Plus administered?

Iverhart Plus pork-liver flavored chewable is administered orally once a month, on the same day of every month, all year round. Monitor that the entire chewable is swallowed. Determined by the dog's weight, a recommended box and dosage is administered. See the dosage chart below:

Dog's Weight (lbs.) Color Box Ivermectin (mg) Pyrantel (mg)
Iverhart Plus up to 25 lbs. Blue 68 57
Iverhart Plus 26 - 50 lbs. Green 136 114
Iverhart Plus 51 - 100 lbs. Brown 272 227
What are the precautions of which you should be aware?

Every dog must take a mandatory test for heartworm disease before using Iverhart Plus or any preventative therapeutic program.

What are the side effects of Iverhart Plus for dogs of which you should be aware?

Iverhart Plus's most common adverse reactions reported are vomiting, lethargy, staggering, mydriasis, convulsions, hypersalivation, decreased appetite, and diarrhea.

Frequently Asked Questions
  1. What is the difference between Iverhart Plus and Iverhart Max?

    Both Iverharts contain Pyrantel and Ivermectin that prevent and kill hookworms, roundworms, and controls heartworms. Iverhart Max contains a third ingredient, Praziquantel, that is fatal for a fourth parasite - tapeworms.

  2. Does Iverhart Plus kill fleas?

    Iverhart Plus is labeled for heartworm prevention, roundworms, and hookworms. One bite may infect fleas and ticks, too.

  3. What do Iverhart Plus reviews say?

    Iverhart Plus reviews rate 4.5+ out of 5 stars. Most reviewers say that Iverhart Plus is accessible and effective for their furry best friend. A monthly flavored chewable protect their dog from fatal heartworms and its relative disease.

  4. What is the difference between Iverhart Plus for large dogs and small dogs?

    Just the major difference between the dosages of the two powerful active ingredients - Ivermectin and Pyrantel. Small dogs are given 68 mg of Ivermectin and 57 mg Pyrantel. Large dogs are given 272 mg of Ivermectin and 227 mg of Pyrantel.

  5. Can I get Iverhart Plus without a prescription?

    In the United States, purchasing heartworm preventive requires a prescription, according to the AHS (American Heartworm Society), which owners use to buy medication from their veterinarian or through a U.S. pharmacy.

Concluding Thoughts

The most important thing that you should know about Iverhart Plus is its motto every dog, everywhere, deserves protection from deadly heartworms!.

DISCLAIMER: FDA law restricts Iverhart Plus only on order or prescription of a licensed veterinarian for the best pet health care advice. Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427, if this is a suitable product for your pet and your home. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA-approved and/or EPA regulated when and as required by law.

Side Effects & Warnings

Side effects can include vomiting or diarrhea within 24 hours of dosing, as well as depression/lethargy, loss of appetitie, staggering, convulsions, and hypersalivation. Herding breed dogs have been reported to be more prone to experiencing the side effects of Iverhart Plus.


Ivermectin and Pyrantel Pamoate


Administer Iverhart Plus once every month. The tablets are intended to be chewed, not swallowed. Break the tablets up, if dog does not want to chew.

Iverhart Plus can be given to your dog by hand, mixed with a small amount of food, or placed in the back of your dog’s mouth for forced swallowing.

Watch your dog closely after giving them Iverhart Plus to be sure the entire dose has been swallowed. If your dog has not completely swallowed the full dose, give them one more full recommended dose as soon as possible

Need Help? Call 1-866-893-0306