Requires Rx

Free delivery

Typical Consumer

Members Save $/yr

Member Price
Cannot be combined with other offers

Every time a new member signs up, we will donate a FREE membership to a Best Friends adopted animal. Best Friends is America's largest animal sanctuary.

Get all these benefits with $139.95 annual membership


Our customers typically save close to $200/yr when purchasing preventatives as members of PetPlus.

PetPlus is a membership plan that gives you wholesale pricing on preventatives, supplements and speciality foods.
With Free Shipping always, no minimums.

Why Become A Member? Additional Ways To Save With PetPlus

Typical Annual Savings "For Your Pet

Typical Annual Cost $40 $190 $95 $112 $200
PetPlus Annual Cost $12 $110 $55 $68 $150
  Sample Annual PetPlus Savings $28 $80 $40 $44 $65
Typical Annual Cost
PetPlus Annual Cost
Sample Annual PetPlus Savings

We're Here to Help You Every Step of the Way

average savings

$242 / YR

Wholesale Prices on Pet Medication & Supplements
Free 24/7 Pet Help provided by whiskerDocs
Wholesale Prices on RX & Premium Foods and Treats
Convenient Medication Pickup Option
Free Delivery on Medication
Product Description

Heart disease can seem scary, especially when it's affecting your beloved pet.Digoxin is a cardiac glycoside heart medication primarily prescribed for managing certain abnormal heart rhythms and congestive heart failure in humans. However, it's also employed off-label in veterinary medicine to address various heart conditions in pets, including cats, dogs, ferrets, and horses.

This medication is typically administered orally as a tablet or liquid and can be given with or without food. In hospital settings, an injection form is also available for immediate use.

In cases where vomiting occurs, especially on an empty stomach, administering the medication with food or a treat can help mitigate this issue. However, pet owners must carefully measure liquid doses to prevent accidental overdose.

Effectiveness and Missed Doses - Pets usually exhibit the medication's effectiveness within 1 to 2 hours of administration. If a dose is missed, it should be administered as soon as remembered. However, skipping the missed one is advised if it's close to the next scheduled dose.

  • Side Effects and Monitoring -Common side effects of digoxin include vomiting, diarrhea, lack of appetite, weight loss, tiredness, and behavior changes. More severe reactions, such as collapse or muscle weakness, require immediate attention. While these effects typically subside within a few days, they may linger longer in pets with liver or kidney disease.

  • Precautions and Interactions -Digoxin is not suitable for pets allergic to it or those with excessive levels in their bloodstream. Caution is advised when using it in animals with specific conditions like certain arrhythmias, hypertrophic cardiomyopathy, kidney disease, heart failure, or subaortic stenosis. Additionally, pet parents exercise caution when administering digoxin alongside various other medications, including alprazolam, beta-blockers, calcium channel blockers, fluoxetine, NSAIDs, and thyroid supplements.

  • Monitoring and Storage -Regularly monitoring serum digoxin levels, appetite, body weight, electrolytes, kidney function, and electrocardiograms during therapy is necessary. The medication should be stored at room temperature (59F to 86F or 15C to 30C) and shielded from light.

In case of an overdose or adverse reactions, contacting the veterinary office immediately is crucial. They can guide further steps, including directions for reaching an emergency facility if the veterinary office is unavailable. It's imperative to follow their instructions diligently to ensure the pet's well-being.

Side Effects & Warnings

Your pet may experience decreased appetite, vomiting, diarrhea, depression, lack of coordination, and weakness. Contact your veterinarian if any symptom seems worrisome.


Digoxin 0.125 mg and .25 mg


Use as directed by your veterinarian.

Need Help? Call 1-866-893-0306