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Product Description

Clindamycin, an FDA-approved antibiotic medication, is pivotal in veterinary medicine, addressing a spectrum of pet infections. Administered primarily in hydrochloride capsules or oral liquid, its versatility makes it a valuable tool in treating various conditions.

Clindamycin is a broad-spectrum, orally administered, prescription antibiotic that treats bacterial infections and some protozoan infections, such as babesiosis and toxoplasmosis, in soft tissue, bone, and teeth.

Since bacteria require proteins to develop and reproduce, Clindamycin targets those proteins. It prevents the spread of infection, giving the immune system the support it needs to kill the bacteria. In high doses, Clindamycin has the ability to kill bacteria and protozoa directly.

Mechanism of Action:

Clindamycin, classified as a lincosamide antibiotic, disrupts bacterial protein synthesis. This mechanism targets gram-positive aerobic and anaerobic bacteria, providing a broad-spectrum defense against infections. Its efficacy extends to skin, dental, bone, respiratory, and anaerobic infections.

The primary target of Clindamycin is the bacterial ribosome, which interferes with the synthesis of essential proteins. It disrupts the elongation phase of protein synthesis by binding to the 50S subunit of the bacterial ribosome, preventing the formation of peptide bonds. This interruption impairs the bacteria's ability to grow, replicate, and sustain their structural integrity.

Clindamycin exhibits a notable affinity for gram-positive aerobic bacteria, including Staphylococcus and Streptococcus species. Its effectiveness against these organisms makes it particularly valuable in treating skin, dental, and respiratory infections commonly caused by such bacteria.

Administration and Dosage:

Oral dosing is the common route of administration, although the medication's bitter taste may require innovative approaches. Proper dosage, under the veterinarian's instructions, is essential to avoid adverse effects such as bloody diarrhea, liver dysfunction, and potentially fatal diarrhea.

Interactions and Monitoring:

Clindamycin interacts with other medications, particularly neuromuscular blocking agents. Pet owners must communicate all concurrent medications to the veterinarian to prevent complications. Monitoring for allergic reactions is crucial, especially in pets with pre-existing liver disease or compromised kidney function.

Adverse Effects and Special Considerations:

Pets may experience adverse effects, emphasizing the importance of vigilant observation. Esophageal injury has been reported, highlighting the need for careful administration. Clindamycin is contraindicated in pets with a history of allergic reactions to lincosamide antibiotics.

Action Against Anaerobic Bacteria:

Beyond its impact on aerobic bacteria, Clindamycin also demonstrates efficacy against anaerobic bacteria. Anaerobic infections, often found in deep-seated wounds or dental abscesses, are effectively targeted by Clindamycin, broadening its spectrum of coverage.

Clindamycin's effectiveness as a broad-spectrum antibiotic in veterinary medicine is undeniable. Pet owners must follow their veterinarian's instructions diligently, be aware of potential drug interactions, and monitor their pets closely for any signs of adverse reactions. Open communication with the veterinarian is imperative for a successful treatment plan and the well-being of the furry companions.

Side Effects & Warnings

Seek emergency veterinary aid if your pet experiences an allergic reaction such as, hives, difficulty breathing, swelling of the face, lips, tongue or throat. Consult veterinarian if your pet experiences watery or bloody diarrhea, fever, chills, body aches, nausea, stomach pain, loss of appetite, dark urine, jaundice, urinating less than usual or not at all, fever, headache, blistering or peeling of the skin, or anything out of the ordinary.

Interactions may occur with vitamins and supplements, erythromycin, or cyclosporine.


Clindamycin Hydrochloride


Administer Clindamycin to the exact specifications prescribed by veterinarian. Give Clindamycin orally with water.


All Weights: 2.5mg-15mg per pound every 12 hours for a maximum of 28 days


All Weights: 5mg-15mg per pound once every 24 hours

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